2023
Vijendra Sharma, Mauricio M. Oliveira, Rapita Sood, Abdessattar Khlaifia, Danning Lou, Mehdi Hooshmandi, Tzu-Yu Hung, Niaz Mahmood, Maya Reeves, David Ho-Tieng, Noah Cohen, Po-chieh Cheng, Mir Munir A. Rahim, Masha Prager-Khoutorsky, Randal J. Kaufman, Kobi Rosenblum, Jean-Claude Lacaille, Arkady Khoutorsky, Eric Klann, Nahum Sonenberg. mRNA translation in astrocytes controls hippocampal long-term synaptic plasticity and memory. PNAS. 2023 (In Press)
Raghd Al Olabi, Abd El Aziz Hendy, Mohamad B. Alkassab, Karla Alnajm, Manahel Elias, Mary Ibrahim, James R. Carlyle, Andrew P. Makrigiannis, Mir Munir A. Rahim. The inhibitory NKR-P1B receptor regulates NK cell-mediated mammary tumour immunosurveillance in mice. Oncoimmunology. 2023; 12(1): 2168233.
2022
Michal Scur, Ahmed B. Mahmoud, Farah Abdalbarri, Iona Stylianides, Daniel M. Luna, Gayani Gamage, Aaron Woblistin, Alexa N. M. Wilson, Haggag M. Zein, Ashley Stueck, Andrew Wight, Brendon D. Parsons, Mir Munir A. Rahim, James R. Carlyle and Andrew P. Makrigiannis. Metabolic Programming Via a C-type Lectin Receptor Protects Alveolar Macrophages From Foam Cell Formation and Death by Lipotoxicity. Nature Communications. 2022; 13: 7272.
Seyed Iraj Sadraei, Greg Yousif, S. Maryamdokht Taimoory, Emmanuel Igbokwe, Samaneh Mehri, Raghd Alolabi, Jason Toma, Mir Munir A. Rahim*, John F. Trant*. The total synthesis of proposed immunoactive glycolipids from S. pneumoniae and a reevaluation of their immunological activity. ChemBiochem. 2022; 23: e202200361. *co-corresponding authors
Eddie Grimmett; Bayan Al-Share; Mohamad Basem Alkassab; Ryan Weng Zhou; Advait Desai; Mir Munir A. Rahim*, Indryas Woldie*. Cancer Vaccines: Past, Present and Future; A review Article. Discover Oncology. 2022; 13: 31. *co-corresponding authors
Haggag Salah Zein, Elias Abou-Samra, Michal Scur, Bishal Dasgupta, Alex Gutsol, Clayton Hall, Turki Abujamel, Daniel Medina-Luna, Gayani Gamage, Tessa Pellino, Mir Munir A. Rahim, Alexander Steinle, Brendon D. Parsons, and Andrew P. Makrigiannis. Clr-f Expression Regulates Kidney Immune and Metabolic Homeostasis. Scientific Reports. 2022; 12: 4834.
2020
Andrew Wight, Brendon D. Parsons, Mir Munir A. Rahim, Andrew P. Makrigiannis. A central role for
Ly49 receptors in NK cell memory. Journal of Immunology. 2020; 204: 2867-2875.
Mir Munir A. Rahim*, Brendon D. Parsons*, Emma L. Price, Patrick D. Slaine, Becca L. Chilvers, Gregory S. Seaton, Andrew Wight, Sayanti Dey, Shannen L. Grandy, Lauryn E. Anderson, Natalia Zamorano Cuervo, Nathalie Grandvaux, Marta M. Gaglia, Alyson A. Kelvin, Denys A. Khaperskyy, Craig McCormick, Andrew P. Makrigiannis. Defective influenza A virus RNA products mediate MAVS-dependent upregulation of human leukocyte antigen class I proteins. Journal of Virology. 2020; 94: e00165-20. *equal contribution
2019
Oscar A. Aguilar, Isabella S. Sampaio, Mir Munir A. Rahim, Jackeline D. Samaniego, Mulualem E. Tilahun, Mithunah Krishnamoorthy, Branka Popović, Marina Babić, Astrid Krmpotić, Bebhinn Treanor, David H. Margulies, David S. J. Allan, Andrew P. Makrigiannis, Stipan Jonjić, James R. Carlyle. Mouse Cytomegalovirus m153 Protein Stabilizes Expression of the Inhibitory NKR-P1B Ligand Clr-b. Journal of Virology. 2019; 94(1): e01220-19.
Elias Abou-Samra, Zachary Hickey, Oscar A. Aguilar, Michal Scur, Ahmad Bakur Mahmoud, Sergey Pyatibrat, Megan M. Tu, Jeffrey Francispillai, Arthur Mortha, James R. Carlyle, Mir Munir A. Rahim*, and Andrew P. Makrigiannis*. NKR-P1B expression on gut-associated innate lymphoid cells is required for the control of gastrointestinal tract infections. Cellular and Molecular Immunology. 2019; 16 (11): 868-877. *co-corresponding authors
2018 and earlier
Andrew Wight, Ahmad B. Mahmouda, Michal Scur, Megan M. Tu, Mir Munir A. Rahim, Subash Sad, and Andrew P. Makrigiannis. Critical Role for Class I MHC Receptors in Adaptive Natural Killer Cell Memory. PNAS. 2018 ;115(45):11579-11584.
Megan M. Tu, Mir Munir A. Rahim, Céline Sayed, Ahmad Bakur Mahmoud and Andrew P. Makrigiannis. Immunosurveillance and Immunoediting of Breast Cancer via Class I MHC Receptors. Cancer Immunology Research. 2017;5(11):1016.
Oscar A. Aguilar, Richard Berry, Mir Munir A. Rahim, Johanna J. Reichel, Branka Popović, Miho Tanaka, Zhihui Fu, Gautham R. Balaji, Timothy N.H. Lau, Megan M. Tu, Christina L. Kirkham, Ahmad Bakur Mahmoud, AruzMesci, Astrid Krmpotić, David S.J. Allan, Andrew P. Makrigiannis, Stipan Jonjić , Jamie Rossjohn, James R. Carlyle. A Viral Immunoevasion Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family. Cell. 2017;169(1):58-71.
Mir Munir A. Rahim. The downside of human natural killer cell diversity in viral infection revealed by mass cytometry. Annals of Translational Medicine. 2016;4(24):546. *Invited commentary.
Mir Munir A. Rahim*, Andrew Wight, Ahmad B. Mahmoud, Oscar A. Aguilar, Sueng-Hwan Lee, Silvia M. Vidal, James R. Carlyle, Andrew P. Makrigiannis. Expansion and protection by a virus-specific NK cell subset lacking the expression of inhibitory NKR-P1B receptor during murine cytomegalovirus infection. Journal of Immunology. 2016;197(6):2325-37. *corresponding author
Mir Munir A. Rahim, Frederic Vigneault, William Zerges. The RNA structure of cis-acting translational elements of chloroplast psbC mRNA in Chlamydomonas reinhardtii. Frontiers in Plant Science. 2016;7:828.
Ahmad Bakur Mahmoud, Megan M. Tu, Andrew Wight, Haggag S. Zein, Mir Munir A. Rahim, Seung-Hwan Lee, Harman S. Sekhon, Earl G. Brown, Andrew P. Makrigiannis. Influenza Virus Targets Class I MHC-Educated NK Cells for Immunoevasion. PLoS Pathogens. 2016;12(2):e1005446.
Mir Munir A. Rahim, Andrew P. Makrigiannis. Ly49 receptors: Evolution, Genetic Diversity, and Impact on Immunity. Immunological Reviews. 2015;267(1):137-47.
Peter Chen, Oscar A. Aguilar, Mir Munir A. Rahim, David S.J. Allan, Jason H. Fine, Christina L. Kirkham, Vicky Kartsogiannis, Matthew Gillespie, Andrew P. Makrigiannis, James R. Carlyle. Genetic investigation of MHC-independent missing-self recognition by mouse NK cells. Journal of Immunology. 2015;194(6):2909-18.
Mir Munir A. Rahim, Peter Chen, Amelia N. Mottashed, Ahmad B. Mahmoud, Midhun J. Thomas, Qinzhang Zhu, Colin G. Brooks, Vicky Kartsogiannis, Matthew T. Gillespie, James R. Carlyle, Andrew P. Makrigiannis. Mouse NKR-P1B:Clr-b recognition system is a negative regulator of innate immune responses. Blood. 2015;125(14):2217-27.
Patricia D.A. Lima, Megan M. Tu, Mir Munir A. Rahim, Annie R. Peng, Anne B. Croy, Andrew P. Makrigiannis.Ly49 receptors activate angiogenic mouse DBA+ uterine natural killer cells. Cellular & Molecular Immunology. 2014;11(5):467-76.
Megan M. Tu, Ahmad Bakur Mahmoud, Andrew Wight, Amelia Mottashed, Simon Bélanger, Mir Munir A. Rahim, Elias Abou-Samra, Andrew P. Makrigiannis. Ly49 family receptor expression is required for cancer immunosurveillance mediated by natural killer cells. Cancer Research. 2014;74(14):3684-94.
Mir Munir A. Rahim*, Megan M. Tu, Ahmad Bakur Mahmoud, Andrew Wight, Elias Abou-Samra, Patricia D. A. Lima, Andrew P. Makrigiannis. Ly49 receptors: Innate and adaptive immune paradigms. Frontiers in Immunology. 2014; 5:145. *corresponding author
Emily McFall, Megan M. Tu, Nuha Abdulhamid Al-Khattabi, Lee-Hwa Tai, Aaron S. St-Laurent, Velina Tzankova, Clayton W. Hall, Simon Belanger, Angela D. Troke, Andrew Wight, Ahmad Bakur Mahmoud, Haggag S. Zein, Mir Munir A. Rahim, James R. Carlyle, and Andrew P. Makrigiannis. Optimized tetramer analysis reveals Ly49 promiscuity for MHC-1 ligands. Journal of Immunology. 2013;191(11);5722-5729.
Mir Munir A. Rahim*, Lee-Hwa Tai*, Angela D. Troke, Ahmad Bakur Mahmoud, Elias Abou Samara, Justin G. Roy, Amelia Mottashed, Nicholas Ault, Chloe Corbeil, Marie-Line Goulet, Haggag S. Zein, Melisa Hamilton-Valensky, Gerald Krystal, William G. Kerr, Noriko Toyama-Sorimachi, and Andrew P. Makrigiannis. Ly49Q positively regulates type I interferon production by plasmacytoid dendritic cells in an immunoreceptor tyrosine-based inhibitory motif-dependent manner. Journal of Immunology. 2013;190(8):3994-4004. *equal contribution.
Mir Munir A. Rahim, Pavel Chrobak, Elena Priceputu, Zaher Hanna and Paul Jolicoeur. Normal development and function but impaired memory phenotype of CD8+ T cells in transgenic mice expression HIV-1 Nef. Virology. 2013;438(2):84-97.
Qiang Zhang, Mir Munir A. Rahim, Megan M. Tu, David Allan, Simon Belanger, Elias Abou-Samra, Harman Sekhon, Todd Fairhead, Haggag S. Zein, Stephen K. Anderson, James R. Carlyle and Andrew P. Makrigiannis. Nkrp1-Clr gene cluster sequence and expression analysis in mouse reveals conservation or organ-specific MHC-independent immunoserveillance. PLoS One. 2012;7(12):e50561.
Simon Bélanger, Megan M. Tu, Mir Munir A. Rahim, Rajen Patel, Lee-Hwa Tai, Angela D. Troke, Brian T. Wilhelm, Josette-Renée Landry, Qinzhang Zhu, Kenneth S.K. Tung, David H. Raulet, Andrew Makrigiannis. Impaired Natural Killer Cell Self-Education and 'Missing-Self' Responses in Ly49-Deficient Mice. Blood. 2012;120(3):592-602.
Peter Chen, Simon Bélanger, Oscar A. Aguilar, Qiang Zhang, Aaron St-Laurent, Mir Munir A. Rahim, Andrew P. Makrigiannis, James R. Carlyle. Analysis of the mouse 129-strain Nkrp1-Clr gene cluster reveals conservation of genomic organization and functional receptor-ligand interactions despite significant allelic polymorphism. Immunogenetics. 2011;63(10):627-40.
Xuefang Xie, Michael D. Stadnisky, Ebony R. Coats, Mir Munir A. Rahim, Alyssa Lundgren, Wenhao Xu, Andrew P. Makrigiannis, Michael G. Brown. MHC class I D(k) expression in hematopoietic and nonhematopoietic cells confers natural killer cell resistance to murine cytomegalovirus. Proc Natl Acad Sci U S A. 2010;107(19):8754-9.
Mir Munir A. Rahim, Pavel Chrobak, Chunyan Hu, Zaher Hanna, Paul Jolicoeur. Adult AIDS-like disease in a novel inducible human immunodeficiency virus type 1 Nef transgenic mouse model: CD4+ T cell activation is Nef dependent and can occur in the absence of lymphophenia. Journal of Virology. 2009;83(22):11830-11846.
Munir Ahmed Rahim, R. K. Saxena, R. Gupta, A. Sheoran, B. Giri. A novel and quick plate assay for acetamidase producers and process optimization for its production by Aspergillus candidus. Process Biochemistry. 2003;38:861-866.